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InvivoGen提供多種重組細胞因子，包括干擾素、白介素、生長/集落刺激因子、類激素細胞因子和腫瘤壞死因子相關(guān)細胞因子。我們的細胞因子來源于大腸桿菌和/或哺乳動物細胞表達系統(tǒng)。各個批次的產(chǎn)品均使用對應的報告細胞以及中和抗體進行功能測試和炎癥。InvivoGen的重組細胞因子以極-具競爭力的價格提供卓-越的品質(zhì)。
主要特點
• 來源于大腸桿菌或哺乳動物細胞（CHO或HEK293）
• 保證生物活性
• 高純度
• 徹-底純化，不含內(nèi)毒素
• 嚴格的質(zhì)量控制
應 用
• 細胞因子檢測和定量分析標準品
• 中和抗體篩選和釋放分析
• 工程化細胞因子篩選和釋放分析
| 產(chǎn)品 | 描述 | 貨號 |
| 源自大腸桿菌的細胞因子 | ||
| Recombinant human CD40L | E. coli-derived recombinant human cytokine,tag-free, with HSA | rcyec-hcd401 |
| Recombinant human G-CSF | E. coli-derived recombinant human cytokine,tag-free, carrier-free | rcyec-hgcsf |
| Recombinant human GM-CSF | E. coli-derived recombinant human cytokine, tag-free, carrier-free | rcyec-hgmcsf |
| Recombinant human IFN-Y | E. coli-derived recombinant human cytokine,tag-free, with HSA | rcyec-hifng |
| Recombinant human IL-1β | E. coli-derived recombinant human cytokine,tag-free, with HSA | rcyec-hil1b |
| Recombinant human IL-3 | E. coli-derived recombinant human cytokine,tag-free, carrier-free | rcyec-hil3 |
| Recombinant human IL-4 | E. coli-derived recombinant human cytokine,tag-free, with HSA | rcyec-hil4 |
| Recombinant human IL-6 | E. coli-derived recombinant human cytokine, tag-free, with HSA | rcyec-hil6 |
| Recombinant human IL-18 | E. coli-derived recombinant human cytokine,tag-free, with HSA | rcyec-hil18 |
| Recombinant human IL-21 | E. coli-derived recombinant human cytokine, tag-free, carrier-free | rcyec-hil21 |
| Recombinant human IL-31 | E. coli-derived recombinant human cytokine,tag-free, carrier-free | rcyec-hil31 |
| Recombinant human IL-33 | E. coli-derived recombinant human cytokine,tag-free, carrier-free | rcyec-hil33 |
| Recombinant human IL-36a | E. coli-derived recombinant human cytokine,tag-free, carrier-free | rcyec-hil36a |
| Recombinant human RANKL | E. coli-derived recombinant human cytokine,tag-free, carrier-free | rcyec-hrankl |
| 為您的抗體研究選擇合適的細胞因子來源 |  |
| 針對不同實驗目標，InvivoGen提供產(chǎn)自大腸桿菌或哺乳動物細胞的高質(zhì)量重組細胞因子，價格極-具競爭力。 • 產(chǎn)自大腸桿菌的細胞因子 是早期抗體篩選的理想選擇（如特異性或結(jié)合分析）。一些細胞因子沒有天然的的復雜糖基化，因此可以由大腸桿菌產(chǎn)生正確折疊且具有生物活性的細胞因子。這些細胞因子常被用作免疫原，以從小鼠或兔子體內(nèi)獲取特異性單克隆抗體(mAb)。然而，用于治療的重組mAb必須用哺乳動物細胞產(chǎn)生的細胞因子進行測試，以確保其有效靶向和中和人類的靶標。 • 產(chǎn)自哺乳動物的細胞因子 具有天然的3D折疊和翻譯后修飾，例如糖基化和二硫鍵模式，這些模式在細菌中難以或不可能重現(xiàn)。通過選擇CHO或HEK293表達的細胞因子，可以加速從早期篩選到臨床開發(fā)的過渡。 | |
| 特色產(chǎn)品 | |
| RECOMBINANT HUMAN IL-18 | RECOMBINANT HUMAN IL-1β |
 |  |
| (A) HEK-BlueTM IL-18 and (B) HEK-BlueTM IL-1β cells were stimulated with increasing concentrations of human (h)IL-18 (produced in E. coli), or hIL-1β (produced in E. coli or CHO cells), respectively. After overnight incubation, the NF-κB-induced SEAP activity was determined using QUANTI-Blue™, a SEAP detection reagent. Data are shown as optical density (OD) at 650 nm (mean ± SEM). | |
| 相關(guān)產(chǎn)品 | 貨號 | |
| Cytokine Agonist Screening Service | cytk-ago | |
| B18R-IFN-a/β inhibitor | inh-b18r | |
| B8R-IFN-y inhibitor | inh-b8r | |
| 產(chǎn)品 | 描述 | 貨號 |
| CYTOKINES PRODUCED IN CHO/HEK293 CELLS | ||
| Recombinant human APRIL | HEK293-derived recombinant human cytokine, His-tag, carrier-free | rcyc-hapril-hs |
| Recombinant human BAFF | CHO-derived recombinant human cytokine, tag-free, carrier-free | rcyc-hbaff |
| Recombinant human CD40L | CHO-derived recombinant human cytokine, tag-free, carrier-free | rcyc-hcd40l |
| Recombinant human EPO | CHO-derived recombinant human cytokine, tag-free, carrier-free | rcyc-hepo |
| Recombinant human GM-CSF | CHO-derived recombinant human cytokine, tag-free, carrier-free | rcyc-hgmcsf |
| Recombinant human IFN-α2b | CHO-derived recombinant human cytokine, tag-free, with HSA | rcyc-hifna2b-1 |
| Recombinant human IFN-α10 | CHO-derived recombinant human cytokine, tag-free, with HSA | rcyc-hifna10-1 |
| Recombinant human IL-1β | CHO-derived recombinant human cytokine, tag-free, carrier-free | rcyc-hil1b |
| Recombinant human IL-2 | CHO-derived recombinant human cytokine, tag-free, carrier-free | rcyc-hil2-01 |
| Recombinant human IL-4 | CHO-derived recombinant human cytokine, tag-free, carrier-free | rcyc-hil4 |
| Recombinant human IL-5 | CHO-derived recombinant human cytokine, tag-free, carrier-free | rcyc-hil5 |
| Recombinant human IL-7 | CHO-derived recombinant human cytokine, tag-free, carrier-free | rcyc-hil7 |
| Recombinant human IL-9 | CHO-derived recombinant human cytokine, tag-free, carrier-free | rcyc-hil9 |
| Recombinant human IL-10 | HEK293-derived recombinant human cytokine, tag-free, carrier-free | rcyc-hil10 |
| Recombinant human IL-11 | CHO-derived recombinant human cytokine, tag-free, carrier-free | rcyc-hil11 |
| Recombinant human IL-12 | CHO-derived recombinant human cytokine, tag-free, with HSA | rcyc-hil12 |
| Recombinant human IL-13 | CHO-derived recombinant human cytokine, tag-free, carrier-free | rcyc-hil13 |
| Recombinant human IL-15 | CHO-derived recombinant human cytokine, tag-free, carrier-free | rcyc-hil15 |
| Recombinant human IL-16 | HEK293-derived recombinant human cytokine, tag-free, carrier-free | rcyc-hil16-01 |
| Recombinant mouse IL-16 | HEK293-derived recombinant mouse cytokine, tag-free, carrier-free | rcyc-mil16-01 |
| Recombinant human IL-17A | CHO-derived recombinant human cytokine, tag-free, carrier-free | rcyc-hil17a |
| Recombinant human IL-20 | CHO-derived recombinant human cytokine, tag-free, carrier-free | rcyc-hil20 |
| Recombinant human IL-22 | HEK293-derived recombinant human cytokine, tag-free, carrier-free | rcyc-hil22 |
| Recombinant human IL-23 | CHO-derived recombinant human cytokine, tag-free, carrier-free | rcyc-hill23 |
| Recombinant human IL-25 | HEK293-derived recombinant human cytokine, tag-free, carrier-free | rcyc-hil25 |
| Recombinant human IL-29 | HEK293-derived recombinant human cytokine, tag-free, carrier-free | rcyc-hil29 |
| Recombinant human TGF-β | HEK293-derived recombinant human cytokine, tag-free, with HSA | rcyc-htgfb1 |
| Recombinant human TL1A | CHO-derived recombinant human cytokine, tag-free, carrier-free | rcyc-htl1a |
| Recombinant human TNF-α | CHO-derived recombinant human cytokine, tag-free, with HSA | rcyc-htnfa |
| Recombinant human TPO | CHO-derived recombinant human cytokine, tag-free, carrier-free | rcyc-htpo |
| Recombinant human TSLP | CHO-derived recombinant human cytokine, His-tag, carrier-free | rcyc-htslp-hs |
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